Talents

Single Target:

3210021
2210021 – Pre patch. T1 Talents are close so best is to sim all 3.

Multi Target:

2210023 – standard AoE
2230023 – with resets

Gameplay

Combo Builder (filler):

Fan of Knives (2+ targets OR at full stacks of Hidden Blades) > Mutilate

Finisher (single target):

Rupture* > Envenom

*additional requirements in the Notes section

Finisher (multi target):

Crimson Tempest* > Rupture* > Envenom

*additional requirements in the Notes section

Opener (single target):

pre-pull:
Marked for Death (if talented), Potion

pull:
Garrote – Mutilate – Mutilate – Rupture – Vendetta – Toxic Blade -…- Vanish – Garrote with ~6 sec remaining on Garrote

*replace the first Builder after Vendetta with Fan of Knives if you use Hidden Blades.

Opener (multi target):

pre-pull:
Marked for Death (if talented), Potion

pull:
Garrote (up to 3 targets) – Build to 4+- Crimson Tempest – Build to 4+- Rupture – Vendetta – Toxic Blade -…- Vanish – Garrote with ~6 sec remaining on Garrote

Rotation:

Use Marked for Death on low Combo Points.
Use Vendetta on cooldown.
Use Vanish if Garrote has ~6 seconds left .
Use Toxic Blade on cooldown.
Use Blindside if you have a proc and not on full cp, always below 30%.

Use Garrote if it has ~6 secs left (and is not empowered) and you are not on full cp.
Use Garrote if it has ~1 secs left.

Use Finisher According to Finisher priority with 4+ Combo Points.
Use Builder According to Builder priority with less then full Combo Points.

Notes:

Crimson Tempest – refresh with 2 or less seconds remaining.
Rupture – refresh with less then ~5-7 seconds remaining.
Rupture – on all Targets.
Garrote – on all Targets.

Talents

Single Target:

2010022
2010023 – for pre patch ONLY under the condition that you use Mantle of the master Assassin and T21 4p (likely without T20).

Multi Target:

2010022 – default choice
2010021 – alternative

Gameplay

Combo Builder (filler): 

Pistol Shot* > Sinister Strike

*additional requirements in the Notes section

Finisher (single target + multi target):

Roll the Bones* > Between the Eyes* > Dispatch

*additional requirements in the Notes section

Reroll logic

Grand Melee or Ruthless Precision or any 2+ buffs.

Opener (single target + multi target):

pre-pull:
Marked for Death (if talented), Potion, Adrenalin Rush
Note: Adrenalin Rush will put you out of stealth, you can enter stealth or open with Sinister Strike.

pull:
Ambush – build to 5+ – Roll the Bones
*use Blade Rush after Ambush on 2+ targets

Rotation:

Use Adrenaline Rush on cooldown.
Use Marked for Death on low Combo Points.
Use Blade Flurry on 2+ targets.
Use Blade Rush on cooldown in single target
Use Blade Rush during Blade Flurry on 2+ targets.

Use Finisher according to Finisher priority if you have 5 Points. Reduce the Amount by 1 if Broadside or Opportunity is up(by 2 if both are up).
Use Builder according to the Builder priority with less then full Combo Points.

Notes:

Pistol Shot – only if it procs and you have 4 or less cp.(3 when Broadside or Opportunity is up, 2 if both are up)
Roll the Bones – refresh if less then 3 seconds remaining or you have the wrong buffs (see reroll logic)
Between the Eyes – only if Ruthless Precision is up
Vanish – utility cooldown without Mantle of the master Assassin
Vanish – Use it before KS/BR if you use Mantle of the master Assassin

Talents

Single Target:

2330031

Multi Target:

2320012

Gameplay

Combo Builder:

Shuriken Storm (3+ targets) > Shadowstrike > Shuriken Storm (2 targets) > Backstab

Finisher (single target):

Nightblade* (Not during Shadow Dance) > Secret Technique* (during Symbols of Death) > Eviscerate

*additional requirements in the Notes section

Finisher (multi target):

Nightblade* (Not during Shadow Dance) > Secret Technique* > Eviscerate

*additional requirements in the Notes section

Opener (single target):

pre pull:
Marked for Death (if talented), Potion, Shadow Blades

pull:
Shadowstrike – Nightblade – Symbols of Death – Shadow Dance – Shadowstrike – Shadowstrike – Eviscerate – Shadowstrike – Shadowstrike – Eviscerate – Shadow Dance…
*use Secret Technique instead of the first Evi if you have it talented

Opener (multi target):

pre pull:
Marked for Death (if talented), Potion, Shadow Blades

pull:
Shadowstrike – Nightblade – Symbols of Death – Shadow Dance
Shadowstrike/Shuriken Storm depending on target count.
Finish with 5+. Use Secret Technique as first Finisher in dance, Eviscerate for the following.

Rotation:

Use Symbols of Death on CD.
Use Marked for Death on low Combo Points.
Use Shadow Blades on CD.
Use Vanish with 1 or less secounds of Find Weakness remaining.

Use Shadow Dance with 2 or less Combo Points when Symbols of Death is up.
Use Shadow Dance with 2 or less Combo Points when you are about to cap on charges.

Use Finisher according to Finisher priority if you have 4+ Combo Points(MfD) or 5+ with (DS).
Use Builder according to the Builder priority with less then full Combo Points.

Notes:

Nightblade – refresh it with less then 4,2 sec remaining (Mfd) or less then 4,8 sec remaining (DS).
Nightblade (exception) – refresh it shortly before symbols comes up if the duration is to low(less then remaining cooldown + 10).
Nightblade – on all targets if they survive for 12+ secounds.
Secret Technique – Preferably use during Shadow Dance, use on CD with more targets due to cdr.

Disclaimer:

Rotation and Talent choice can be slightly different in the pre-patch.

Talent Notation:

Talents are distinguished by talent number in row order. 0 signifies free choice.

NOTE: The shown talent is an Example, the talent for your specification can be found in the Talent section of each spec.

Therefore if the talents are listed as:

• 2010032

that means that you need to pick:

• In row 1, take talent number 2
• In row 2, take any talent
• In row 3, take talent number 1
• In row 4, take any talent
• In row 5, take any talent
• In row 6, take talent number 3
• In row 7, take talent number 2